Boubelík M, Plachý J, Vilhelmová M, Spaténková Z
Folia Biol (Praha). 1982;28(5):344-9.
Normal mouse sera from non-immunized individuals of different strains gave high titres of "natural" antibodies which agglutinated RBC's of different inbred lines of chickens. Normal mouse sera of A strain and its congenic lines agglutinated RBC's of all chicken lines whereas normal sera of B10 strain and its congenic lines did not react with RBC's of Iowa A line. Normal sera of other mouse strains behaved similarly. The different reactivity of the congenic chicken lines IA and IC, which are identical in the B complex (MHC) and differ only in erythrocyte antigens of the A blood group system, suggests that natural antibodies may also react with antigens other than the chicken MHC antigens. On the other hand, normal sera from chickens of inbred lines reacted with all erythrocytes of the different mouse strains tested.
来自不同品系未免疫个体的正常小鼠血清产生了高滴度的“天然”抗体，这些抗体能凝集不同近交系鸡的红细胞。A品系及其同源系的正常小鼠血清能凝集所有鸡系的红细胞，而B10品系及其同源系的正常血清与爱荷华A系的红细胞不发生反应。其他小鼠品系的正常血清表现类似。同源鸡系IA和IC在B复合体（MHC）中相同，仅在A血型系统的红细胞抗原上存在差异，它们的不同反应性表明天然抗体也可能与鸡MHC抗原以外的抗原发生反应。另一方面，近交系鸡的正常血清与所测试的不同小鼠品系的所有红细胞都发生反应。
