Kerlin P, Ratnaike R N, Butler R, Grant N G
Am J Dig Dis. 1978 Oct;23(10):940-2. doi: 10.1007/BF01072471.
The prevalence of giardiasis was assessed in 1000 consecutive adult patients undergoing upper-gastrointestinal endoscopy for the usually accepted indications. Patients with upper-gastrointestinal bleeding were excluded. The diagnosis was established by examination of duodenal aspirate and duodenal mucosal impression smears. In 21 patients (2.1%) trophozoites were detected both in the duodenal juice and stained mucosal impression smears. All were treated with metronidazole or tinidazole. In 14 of 16 patients who had subsequent duodenal intubation, eradication of the parasite was confirmed. In five patients previously existent abdominal pain disappeared with clearing of the parasite, and no other cause for their abdominal pain was discovered. A search for Giardia lamblia infestation may be a worthwhile additional procedure at the time of endoscopy when no other cause for abdominal pain is found.
对1000例因通常公认的适应症接受上消化道内镜检查的连续成年患者进行了贾第虫病患病率评估。排除上消化道出血患者。通过十二指肠抽吸物检查和十二指肠黏膜印片涂片进行诊断。在21例患者(2.1%)的十二指肠液和染色黏膜印片中均检测到滋养体。所有患者均接受甲硝唑或替硝唑治疗。在随后进行十二指肠插管的16例患者中的14例中,证实寄生虫已根除。5例既往存在腹痛的患者在寄生虫清除后腹痛消失,且未发现其他腹痛原因。当未发现其他腹痛原因时,在内镜检查时寻找蓝氏贾第鞭毛虫感染可能是一项值得进行的额外检查。