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贾第虫病的患病率:一项在上消化道内镜检查中的研究

Prevalence of Giardiasis: a study at upper-gastrointestinal endoscopy.

作者信息

Kerlin P, Ratnaike R N, Butler R, Grant N G

出版信息

Am J Dig Dis. 1978 Oct;23(10):940-2. doi: 10.1007/BF01072471.

DOI:10.1007/BF01072471
PMID:717353
Abstract

The prevalence of giardiasis was assessed in 1000 consecutive adult patients undergoing upper-gastrointestinal endoscopy for the usually accepted indications. Patients with upper-gastrointestinal bleeding were excluded. The diagnosis was established by examination of duodenal aspirate and duodenal mucosal impression smears. In 21 patients (2.1%) trophozoites were detected both in the duodenal juice and stained mucosal impression smears. All were treated with metronidazole or tinidazole. In 14 of 16 patients who had subsequent duodenal intubation, eradication of the parasite was confirmed. In five patients previously existent abdominal pain disappeared with clearing of the parasite, and no other cause for their abdominal pain was discovered. A search for Giardia lamblia infestation may be a worthwhile additional procedure at the time of endoscopy when no other cause for abdominal pain is found.

摘要

对1000例因通常公认的适应症接受上消化道内镜检查的连续成年患者进行了贾第虫病患病率评估。排除上消化道出血患者。通过十二指肠抽吸物检查和十二指肠黏膜印片涂片进行诊断。在21例患者(2.1%)的十二指肠液和染色黏膜印片中均检测到滋养体。所有患者均接受甲硝唑或替硝唑治疗。在随后进行十二指肠插管的16例患者中的14例中,证实寄生虫已根除。5例既往存在腹痛的患者在寄生虫清除后腹痛消失,且未发现其他腹痛原因。当未发现其他腹痛原因时,在内镜检查时寻找蓝氏贾第鞭毛虫感染可能是一项值得进行的额外检查。

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Prevalence of Giardiasis: a study at upper-gastrointestinal endoscopy.贾第虫病的患病率:一项在上消化道内镜检查中的研究
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[Investigation of the Giardia lamblia infection rate using whole gut lavage fluid].[使用全肠道灌洗液体调查蓝氏贾第鞭毛虫感染率]
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引用本文的文献

1
Diagnostic yield of duodenal aspirate for G. lamblia and comparison to duodenal mucosal biopsies.十二指肠抽吸物对蓝氏贾第鞭毛虫的诊断率及与十二指肠黏膜活检的比较。
Dig Dis Sci. 2003 Mar;48(3):605-7. doi: 10.1023/a:1022513405603.
2
Genetic studies in human and murine giardiasis.人类和鼠类贾第虫病的遗传学研究。
Gut. 1980 May;21(5):397-401. doi: 10.1136/gut.21.5.397.
3
Giardia--diagnosis, clinical course and epidemiology. A review.贾第虫——诊断、临床病程及流行病学。综述。

本文引用的文献

1
EPITHELIAL AND OTHER MUCOSAL LESIONS OF THE JEJUNUM IN GIARDIASIS. JEJUNAL BIOPSY STUDIES.贾第虫病空肠的上皮及其他黏膜病变。空肠活检研究。
Bull Johns Hopkins Hosp. 1964 Nov;115:389-406.
2
The incidence of Giardia lamblia infestation of children in Victoria.
Med J Aust. 1959 Sep 26;46(2):438-40. doi: 10.5694/j.1326-5377.1959.tb129163.x.
3
The experimental transmission of human intestinal protozoan parasites. II. Giardia lamblia cysts given in capsules.人体肠道原生动物寄生虫的实验性传播。II. 以胶囊形式给予的蓝氏贾第鞭毛虫包囊。
Epidemiol Infect. 1992 Aug;109(1):1-22.
Am J Hyg. 1954 Mar;59(2):209-20. doi: 10.1093/oxfordjournals.aje.a119634.
4
Epidemic giardiasis.流行性贾第虫病
N Engl J Med. 1969 Oct 9;281(15):853. doi: 10.1056/nejm196910092811521.
5
Growth retardation, anaemia and infection, with malabsorption and infestation of the bowel. The syndrome of protein-calorie malnutrition in Australian Aboriginal children.生长发育迟缓、贫血和感染,伴有肠道吸收不良和寄生虫感染。澳大利亚原住民儿童的蛋白质 - 热量营养不良综合征。
Med J Aust. 1970 Feb 21;1(8):349-56.
6
A comparative study of four methods for detecting Giardia lamblia in children with diarrheal disease and malabsorption.四种检测腹泻病和吸收不良患儿中蓝氏贾第鞭毛虫方法的比较研究。
Gastroenterology. 1974 Jan;66(1):16-21.
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Giardiasis: a common cause of prolonged diarrhoea in adults.
Med J Aust. 1974 Oct 19;2(16):592-5. doi: 10.5694/j.1326-5377.1974.tb71022.x.
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Giardiasis in American travelers to the Soviet Union.
J Infect Dis. 1974 Sep;130(3):319-23. doi: 10.1093/infdis/130.3.319.
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Giardiasis.
JAMA. 1975 Sep 29;233(13):1362-5.