Sandler R S, Varma V, Herbst C A, Montana G S, Rudnick S A, Fowler W C
Gastrointest Endosc. 1982 Nov;28(4):237-9. doi: 10.1016/s0016-5107(82)73099-8.
Pelvic irradiation has been reported to be a risk factor for colonic malignancy. We performed flexible sigmoidoscopy with serial pinch biopsies in 20 asymptomatic women treated with irradiation for cervical cancer more than 10 years ago in order to determine the feasibility of the technique and to detect late radiation effects. The examination was well tolerated by 14 (70%) of the patients, and the instrument was passed to 40 cm in 14 (74%) of 19 women. Abnormal mucosal or vascular changes were found in 12 (60%) and nonspecific microscopic abnormalities were seen in 18 (90%) of the 20 women.
据报道，盆腔放疗是结肠恶性肿瘤的一个危险因素。为了确定该技术的可行性并检测晚期放射效应，我们对20名10多年前因宫颈癌接受放疗的无症状女性进行了乙状结肠镜检查及系列钳取活检。14名（70%）患者对检查耐受良好，19名女性中有14名（74%）检查时肠镜插入至40厘米。20名女性中12名（60%）发现黏膜或血管异常改变，18名（90%）发现非特异性镜下异常。
