Marchildon M B, Buck B E, Abdenour G
J Pediatr Surg. 1982 Oct;17(5):620-4. doi: 10.1016/s0022-3468(82)80122-x.
From 1974 to 1981, 139 infants with neonatal necrotizing enterocolitis (NEC) were treated at our institution. Fourteen of these infants had not been fed prior to development of NEC. The unfed infants who developed intestinal necrosis had lower birth weights, were less mature, and had lower Apgar scores. The incidence of respiratory distress syndrome (RDS) and perinatal asphyxia were significantly higher in the entire unfed group. Unfed infants generally had longstanding indwelling umbilical artery catheters. Pneumatosis intestinalis was not often seen in unfed infants, even in those who developed intestinal necrosis and perforation. Anatomic location of the disease as determined at surgery was sometimes atypical. The pathologic lesion present in the intestine of the unfed infant suggested a primarily, if not purely, ischemic etiology.
1974年至1981年期间，我院共治疗了139例新生儿坏死性小肠结肠炎（NEC）患儿。其中14例患儿在发生NEC之前未进行过喂养。发生肠坏死的未喂养患儿出生体重较低，成熟度较差，阿氏评分也较低。整个未喂养组中呼吸窘迫综合征（RDS）和围产期窒息的发生率显著更高。未喂养患儿通常长期留置脐动脉导管。即使在发生肠坏死和穿孔的未喂养患儿中，肠壁积气也不常见。手术时确定的疾病解剖位置有时不典型。未喂养患儿肠道中存在的病理病变提示主要（如果不是纯粹的话）是缺血性病因。
