van der Woude F J, Hoorntje S J, Weening J J, van Overbeek J J, van der Hem G K
Nephron. 1982;32(2):185-7. doi: 10.1159/000182841.
Three patients with rapidly progressive glomerulonephritis due to Wegener's granulomatosis are described. In one patient, acute renal failure was initially the sole manifestation of the disease. Treatment of the two other patients with prednisone and cyclophosphamide resulted in a remarkable recovery of renal function even after a prolonged period of hemodialysis. These cases illustrate that early and sustained treatment with prednisone and cyclophosphamide can restore an adequate renal function in patients with anuria or severe glomerulonephritis due to Wegener's disease.
本文描述了3例因韦格纳肉芽肿导致快速进展性肾小球肾炎的患者。其中1例患者，急性肾衰竭最初是该疾病的唯一表现。另外2例患者接受泼尼松和环磷酰胺治疗后，即使经过长时间的血液透析，肾功能仍显著恢复。这些病例表明，对于因韦格纳病导致无尿或严重肾小球肾炎的患者，早期持续使用泼尼松和环磷酰胺治疗可恢复足够的肾功能。
