Garcia-Rodriguez J A, Garcia-Sanchez J E, Prieto J, Sanchez de S Lorenzo A
Antimicrob Agents Chemother. 1982 Nov;22(5):893-4. doi: 10.1128/AAC.22.5.893.
The activities of pirlimycin (U57930E), lincomycin, clindamycin, erythromycin, josamycin, oleandomycin, and spiramycin were compared against strains of the Bacteroides fragilis group. Pirlimycin was the most active; the 90% minimal inhibitory concentration was 1 microgram/ml, and the activity range was 0.125 to 4 micrograms/ml. This drug was fourfold more active than any of the other drugs, including clindamycin. The minimal bactericidal concentration (range, 0.5 to 16 micrograms/ml) shows that pirlimycin behaves as a bacteriostatic antibiotic.
比较了吡利霉素（U57930E）、林可霉素、克林霉素、红霉素、交沙霉素、竹桃霉素和螺旋霉素对脆弱拟杆菌属菌株的活性。吡利霉素活性最强；90%最小抑菌浓度为1微克/毫升，活性范围为0.125至4微克/毫升。该药物的活性比包括克林霉素在内的其他任何药物都高四倍。最小杀菌浓度（范围为0.5至16微克/毫升）表明吡利霉素表现为一种抑菌性抗生素。
