关于胃泌素、胃液分泌与大鼠佐剂性关节炎之间的关系
On the relationship between gastrin, gastric secretion, and adjuvant arthritis in rats.
作者信息
Rooney P J, Dick W C, Imrie R C, Turner D, Buchanan K D, Ardill J
出版信息
Ann Rheum Dis. 1978 Oct;37(5):432-5. doi: 10.1136/ard.37.5.432.
Abstract
The elevation of plasma immunoreactive gastrin known to occur during the induction of adjuvant-induced arthritis (Rooney et al., 1973) has been shown to be maximal at 7 days after injection. Gastrin administered exogenously accelerated and exacerbated the inflammatory joint disease. Some evidence has been presented that the endogenous immunoreactive gastrin had biological activity in terms of gastric acid secretion.
摘要
已知在佐剂诱导性关节炎诱导过程中出现的血浆免疫反应性胃泌素升高（鲁尼等人，1973年）已表明在注射后7天达到最大值。外源性给予胃泌素会加速并加剧炎性关节疾病。已有一些证据表明内源性免疫反应性胃泌素在胃酸分泌方面具有生物活性。
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