类风湿关节炎患者血清免疫反应性胃泌素。关于其性质、临床特异性及其与胃功能关系的进一步观察。
Serum immunoreactive gastrin in rheumatoid arthritis. Further observations on its identity, clinical specificity, and relationship to gastric function.
作者信息
Rooney P J, Kennedy A C, Gray G H, Sturrock R D, Buchanan K D, Dick W C
出版信息
Ann Rheum Dis. 1976 Jun;35(3):246-50. doi: 10.1136/ard.35.3.246.
Abstract
Serum immunoreactive gastrin is raised in some patients with rheumatoid arthritis (RA). In this paper paired samples taken within 30 minutes of each other show that this phenomenon is reproducible. Dilution curves show identity between gastrin from RA patients and from patients with no RA, and the raised immunoreactive gastrin concentration is demonstrable in patients who do not have chronic atrophic gastritis and in whom both basal and stimulated acid output concentrations are normal. Samples of gastric mucous membrane obtained from the body of the stomach and gastroscopy under direct vision in 18 patients with raised serum immunoreactive gastrin concentrations were normal.
摘要
一些类风湿关节炎（RA）患者的血清免疫反应性胃泌素升高。在本文中，在30分钟内采集的配对样本表明这种现象是可重复的。稀释曲线显示RA患者和非RA患者的胃泌素相同，并且在没有慢性萎缩性胃炎且基础和刺激胃酸分泌浓度均正常的患者中，免疫反应性胃泌素浓度升高是可证实的。从18例血清免疫反应性胃泌素浓度升高患者的胃体获得的胃黏膜样本及在直视下进行胃镜检查的样本均正常。
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