Begley A J, Quinn P
Clin Reprod Fertil. 1982 Sep;1(3):167-75.
Decapacitation factors are components of seminal plasma which modulate the fertilizing ability of spermatozoa. This activity arises from the interaction between cholesterol, phospholipids and a fibronectin-like substance and is delivered via small vesicles in seminal plasma. Its function is to prevent the premature onset of the cascade mechanism known as capacitation and this is achieved through spermatozoal membrane stabilization by maintaining a physiological cholesterol/phospholipid ratio. The study of decapacitation factors may throw light on the aetiology of some forms of hitherto unexplained male infertility and may provide the basis of a specific and reversible method of male contraception.
去能因子是精浆的组成成分，可调节精子的受精能力。这种活性源于胆固醇、磷脂和一种纤连蛋白样物质之间的相互作用，并通过精浆中的小泡传递。其功能是防止称为获能的级联机制过早启动，这是通过维持生理胆固醇/磷脂比例来稳定精子膜实现的。对去能因子的研究可能有助于揭示某些迄今无法解释的男性不育症的病因，并可能为一种特定的、可逆的男性避孕方法提供基础。
