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梭状芽孢杆菌无细胞制剂对林丹的降解作用

Degradation of lindane by cell-free preparations of Clostridium sphenoides.

作者信息

Heritage A D, MacRae I C

出版信息

Appl Environ Microbiol. 1977 Aug;34(2):222-4. doi: 10.1128/aem.34.2.222-224.1977.

DOI:10.1128/aem.34.2.222-224.1977
PMID:71878
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC242623/
Abstract

Cell-free preparation of Clostridium sphenoides degraded the insecticide lindane, the gamma-isomer of 1,2,3,4,5,6-hexachlorocyclohexane, to the gamma-isomer of 3,4,5,6-tetrachloro-1-cyclohexene. The activity appeared to be associated with the membrane fraction and required reduced glutathione. The tetrachlorocy-clohexene intermediate was further metabolized by the membrane fraction to unknown substances.

摘要

无细胞制备的蝶形梭菌可将杀虫剂林丹(1,2,3,4,5,6 - 六氯环己烷的γ - 异构体)降解为3,4,5,6 - 四氯 - 1 - 环己烯的γ - 异构体。该活性似乎与膜部分相关,且需要还原型谷胱甘肽。四氯环己烯中间体被膜部分进一步代谢为未知物质。

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