Rao R H, Vigg B L, Rao K S
J Clin Endocrinol Metab. 1980 Jan;50(1):198-200. doi: 10.1210/jcem-50-1-198.
A study was undertaken to test the effect of pyridoxine supplementation on glucose tolerance in diabetes mellitus. Thirteen adult maturity-onset diabetics were studied. Seven were vitamin B6 deficient, as assessed by the stimulation of erythrocyte glutamic oxaloacetic transaminase in vitro by pyridoxal phosphate. All patients received pyridoxine hydrochloride (40 mg twice daily) for 3 weeks. Pyridoxine supplmentation did not bring about any significant alterations in either the oral glucose tolerance or the insulin response to glucose.
开展了一项研究以测试补充吡哆醇对糖尿病患者葡萄糖耐量的影响。对13名成年迟发型糖尿病患者进行了研究。通过磷酸吡哆醛体外刺激红细胞谷氨酸草酰乙酸转氨酶评估，其中7名患者维生素B6缺乏。所有患者接受盐酸吡哆醇（每日两次，每次40毫克）治疗3周。补充吡哆醇对口服葡萄糖耐量或葡萄糖的胰岛素反应均未产生任何显著改变。
