Kruse-Jarres J D, Bresch M, Lehmann U, Letulé U, Vogel W
Infusionsther Klin Ernahr. 1980 Feb;7(1):25-34.
An automatic regulator aep (artificial endocrine pancreas) has been developed for the extracorporeal blood glucose regulation. After glucose monitoring, the maschine steers an insulin infusion pump by means of adequate algorithms to obtain a glucose balance in labile diabetic inpatients. This system, also called artificial beta-cell, is a closed loop regulatory system with impulses from the actual blood glucose that represents true feedback principles. So far it is preferably used during surgical operations of labile diabetics and for the intensive therapy of patients with pancreatic affections. The clear therapeutic advantages, that have been found in some special medical centres, give hope that technical ways will be found to master the narrow passes and the difficulties in the future.
一种用于体外血糖调节的自动调节人工内分泌胰腺（AEP）已被研发出来。在进行血糖监测后，该机器通过适当的算法操控胰岛素输注泵，以实现不稳定型糖尿病住院患者的血糖平衡。这个系统，也被称为人工β细胞，是一个闭环调节系统，它根据实际血糖产生脉冲信号，体现了真正的反馈原理。到目前为止，它主要用于不稳定型糖尿病患者的外科手术过程以及胰腺疾病患者的强化治疗。在一些特殊医疗中心所发现的明显治疗优势，让人们有望在未来找到技术方法来攻克难关。
