Snyder B D, Hauser W A, Loewenson R B, Leppik I E, Ramirez-Lassepas M, Gumnit R J
Neurology. 1980 Dec;30(12):1292-7. doi: 10.1212/wnl.30.12.1292.
Nineteen (30%) of 63 adult survivors of cardiopulmonary arrest had seizures after admission to the hospital. Eleven of 19 had more than one type of seizure. Myoclonic seizures began within 12 hours of the arrest in eight patients, and after 3 or more days in four patients. Only two (17%) patients with myoclonic seizures survived. Partial seizures usually began within 12 hours of the arrest and were controllable with anticonvulsants; 4 of 12 patients survived. Two of four patients with generalized tonic-clonic seizures survived; one of four with "shivering" lived. Overall, patients with seizures had a survival rate of 32% (6 of 19), compared with 43% for patients without seizures. None of the survivors had recurrent seizures within 6 months after hospital admission.
63名心肺复苏成年幸存者中有19人(30%)在入院后出现癫痫发作。19名患者中有11人出现不止一种类型的癫痫发作。8例患者在心脏骤停后12小时内出现肌阵挛性癫痫发作,4例患者在3天或更长时间后出现。仅有2例(17%)肌阵挛性癫痫发作患者存活。部分性癫痫发作通常在心脏骤停后12小时内开始,可用抗惊厥药物控制;12例患者中有4例存活。4例全身性强直阵挛性癫痫发作患者中有2例存活;4例“颤抖”患者中有1例存活。总体而言,癫痫发作患者的存活率为32%(19例中有6例),无癫痫发作患者的存活率为43%。幸存者中无人在入院后6个月内出现复发性癫痫发作。