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从人类和禽类来源分离的甲型流感病毒H2(亚洲型)血凝素的比较研究。

Comparative study of influenza virus H2 (Asian) hemagglutinins isolated from human and avian sources.

作者信息

Bucher D J, Kharitonenkov I G, Lvov D K, Pysina T V, Lee H M

出版信息

Intervirology. 1980;14(2):69-77. doi: 10.1159/000149165.

DOI:10.1159/000149165
PMID:7193663
Abstract

The hemagglutinin of an influenza virus isolated from a wild duck (Pintail, Anas acuta) in the USSR in 1976 had been found to be antigenically indistinguishable from the hemagglutinin of H2N2 viruses of human origin isolated in 1957. The hemagglutinins from viral preparations of the A/Anas acuta/Primorie/695/76 (H2Nav2) and A/Singapore/1/57 (H2N2) strains were purified by SDS gel chromatography as the subunits HA1 and HA2. Comparison of amino acid compositions and peptide maps of tryptic peptides containing [14C]-carboxymethylcysteine showed a striking degree of similarity between the H2 hemagglutinins.

摘要

1976年在苏联从一只野鸭(针尾鸭,绿头鸭)中分离出的流感病毒的血凝素,在抗原性上被发现与1957年分离出的人类源H2N2病毒的血凝素没有区别。A/绿头鸭/滨海边疆区/695/76(H2Nav2)和A/新加坡/1/57(H2N2)毒株病毒制剂中的血凝素通过SDS凝胶色谱法作为亚基HA1和HA2进行纯化。对含有[14C]-羧甲基半胱氨酸的胰蛋白酶肽的氨基酸组成和肽图进行比较,结果显示H2血凝素之间具有显著的相似程度。

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Comparative study of influenza virus H2 (Asian) hemagglutinins isolated from human and avian sources.从人类和禽类来源分离的甲型流感病毒H2(亚洲型)血凝素的比较研究。
Intervirology. 1980;14(2):69-77. doi: 10.1159/000149165.
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引用本文的文献

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Ecological aspects of influenza A viruses in animals and their relationship to human influenza: a review.动物甲型流感病毒的生态学方面及其与人类流感的关系:综述
J R Soc Med. 1982 Oct;75(10):799-811. doi: 10.1177/014107688207501010.