口服给药后血清、子宫和胎儿的水杨酸盐浓度。
Seral, uterine and fetal salicylate concentrations after oral administration.
作者信息
Grönroos M, Haataja M, Honkonen E, Anttila M
出版信息
Eur J Obstet Gynecol Reprod Biol. 1981 Sep;12(3):167-70. doi: 10.1016/0028-2243(81)90072-1.
PMID:7197641
Abstract
Salicylate concentrations in serum, endometrium, myometrium and fetus were determined 3 h after an oral dose of 1 000 mg of acetylsalicylic acid. The material consisted of 19 females (11 for legal abortion and 8 for operative treatment of fibroids). Tissue salicylate concentrations were at a level at which prostaglandin synthetase is inhibited.
摘要
口服1000毫克乙酰水杨酸3小时后，测定血清、子宫内膜、子宫肌层和胎儿中的水杨酸盐浓度。研究对象为19名女性（11例行合法堕胎，8例行子宫肌瘤手术治疗）。组织水杨酸盐浓度处于抑制前列腺素合成酶的水平。
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