Southam J C
Br J Dermatol. 1981 Dec;105(6):679-84. doi: 10.1111/j.1365-2133.1981.tb00978.x.
The fibrinolytic activity of normal human oral epithelium and abdominal epidermis was studied by two techniques. With fibrinolytic autography, dorsal tongue, ventral tongue, cheek, palate and gingival sulcus epithelium showed fibrinolytic activity but oral gingival epithelium and the epidermis showed no activity. With a fibrin plate technique, potassium thiocyanate extracts of epidermis and oral epithelium all showed strong fibrinolytic activity, but activity in tris buffer extracts was demonstrable only with oral epithelium, and the activity was much weaker. The fact that the tris buffer extractable fibrinolytic activator was demonstrated only in oral epithelium suggests that the presence of this activator in epithelium is related to the type of keratinization and/or its rate of cell turnover.
采用两种技术研究了正常人口腔上皮和腹部表皮的纤溶活性。通过纤溶自显影法，舌背、舌腹、颊、腭和龈沟上皮显示出纤溶活性，但口腔牙龈上皮和表皮未显示活性。采用纤维蛋白平板技术，表皮和口腔上皮的硫氰酸钾提取物均显示出较强的纤溶活性，但仅口腔上皮的三羟甲基氨基甲烷缓冲液提取物显示出纤溶活性，且活性较弱。仅在口腔上皮中证实了三羟甲基氨基甲烷缓冲液可提取的纤溶激活剂，这一事实表明该激活剂在上皮中的存在与角质化类型和/或细胞更新率有关。
