Hellstern P, Keller H E, Weinheimer B, Wesch H
Clin Endocrinol (Oxf). 1978 Oct;9(4):351-6. doi: 10.1111/j.1365-2265.1978.tb02220.x.
Thyroid iodine concentration and total thyroid iodine were determined by an automated technique by means of the ceric arsenious acid reaction in 42 males and 13 females. The thyroids were taken from autopsy material in a region with a low dietary intake. The accuracy of the method to estimate iodine was checked by neutron activation analysis. There was an excellent correlation between the iodine contents of thyroid specimens, when measured by chemical or by activation analysis. The mean iodine concentration was 1.86 mg/g dry weight and was found to be lower than in non-goitrous regions. In goitres, the mean iodine concentration was significantly lower, and the mean total thyroid of normal weight. There was no significant difference in iodine concentration and total iodine between males and females. The thyroid iodine concentration did not depend upon age in adults. The data were log normally distributed. It was established that mean iodine concentrations under 2 mg/g dry weight or 0.45 mg/g fresh weight are to be regarded as an important index of iodine deficiency.
采用铈亚砷酸反应的自动化技术，对42名男性和13名女性测定了甲状腺碘浓度和甲状腺总碘量。甲状腺取自饮食碘摄入量低的地区的尸检材料。通过中子活化分析检查了该方法估计碘的准确性。用化学分析或活化分析测定时，甲状腺标本的碘含量之间存在极好的相关性。平均碘浓度为1.86mg/g干重，发现低于非甲状腺肿地区。在甲状腺肿中，平均碘浓度显著降低，正常重量甲状腺的平均总量也降低。男性和女性之间的碘浓度和总碘量无显著差异。成年人的甲状腺碘浓度不依赖于年龄。数据呈对数正态分布。已确定干重低于2mg/g或鲜重低于0.45mg/g的平均碘浓度应被视为碘缺乏的重要指标。
