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临床医学中研究皮肤微循环的新方法(作者译)

[New ways of studying the cutaneous microcirculation in clinical medicine (author's transl)].

作者信息

Bollinger A, Jäger K

出版信息

Arzneimittelforschung. 1981;31(11a):2015-9.

PMID:7199291
Abstract

Transcutaneous video microscopy opens a way to measure capillary red blood cell speed, to analyzed transcapillary diffusion and pericapillary distribution of Na-fluorescein injected i.v. and to depict the superficial lymphatic capillaries by subepidermal microinjection of FITC-labelled dextran in human skin. The dynamic phenomena may be quantitiated by video densitometers provided the information is stored on video tape. Already, some physiological and clinical data have been obtained. The velocity pattern of erythrocytes in nailfold capillaries is continuous or intermittent with flow stops. Standardized cold provocation tests are useful to evaluate Raynaud's disease. In patients with scleroderma the transcapillary passage of Na-fluorescein is increased, the physiological pericapillary halo partially destroyed and the interstitial distribution of the dye asymmetrical. In primary lymphedema the lymphatic network filled from the deposit of fluorescent dextran extends much more than in healthy controls. Pathological lymphatic microvessels occur.

摘要

经皮视频显微镜检查为测量毛细血管红细胞速度、分析经静脉注射荧光素钠后的跨毛细血管扩散及毛细血管周围分布,以及通过在人体皮肤表皮下微量注射异硫氰酸荧光素标记的葡聚糖来描绘浅表淋巴管开辟了一条途径。如果信息存储在录像带上,动态现象可用视频密度计进行量化。目前已经获得了一些生理和临床数据。甲襞毛细血管中红细胞的速度模式是连续的或间歇性的,伴有血流停止。标准化冷激发试验有助于评估雷诺病。在硬皮病患者中,荧光素钠的跨毛细血管通过率增加,生理性毛细血管周围晕部分破坏,染料的间质分布不对称。在原发性淋巴水肿中,由荧光葡聚糖沉积填充的淋巴管网比健康对照延伸得更多。出现病理性淋巴管微血管。

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1
[New ways of studying the cutaneous microcirculation in clinical medicine (author's transl)].临床医学中研究皮肤微循环的新方法(作者译)
Arzneimittelforschung. 1981;31(11a):2015-9.
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