Mancini A F, Rosito P, Faldella G, Serra L, Vallicelli R, Vecchi V, Vivarelli F, Paolucci G
Med Pediatr Oncol. 1982;10(1):45-51. doi: 10.1002/mpo.2950100108.
Hereditary neuroblastoma in a pair of identical twins is reported. In one of the twins the tumor occurred in fetal life and caused death of the twin before birth; in the other one, the tumor occurred at two months of life as IV-S neuroblastoma in the liver with primary tumor undetected. The unusual clinical course of the latter case is described: twice there was tumor regression, but in spite of treatment, fatal uncontrolled growth occurred. The family history, characterized by neoplasms of dissimilar cell types but without additional cases of neuroblastoma, is also detailed.
报道了一对同卵双胞胎中的遗传性神经母细胞瘤。其中一个双胞胎在胎儿期发生肿瘤，并导致双胞胎在出生前死亡；另一个在出生两个月时发生肿瘤，为肝脏IV-S期神经母细胞瘤，原发肿瘤未被发现。描述了后一例病例不同寻常的临床病程：肿瘤曾两次消退，但尽管接受了治疗，仍发生了致命的、无法控制的生长。还详细介绍了家族病史，其特征为不同细胞类型的肿瘤，但无其他神经母细胞瘤病例。
