Value of central nervous system IgG daily synthesis determination in the diagnosis of multiple sclerosis.

Using laser beam immunonephelometry, we confirmed the value of Tourtellotte's formula in the diagnosis of MS. Moreover, since immunonephelometry presents several advantages, including simplicity, rapidity, and precision, it is a promising technique for the diagnosis of MS. Complicated measurements are not necessary. Determinations take only minutes. The results are reproducible. Mathematics manipulations are simple with readily available computers.