Foucar E, Rosai J, Dorfman R F, Brynes R K
Neurology. 1982 Apr;32(4):365-72. doi: 10.1212/wnl.32.4.365.
Sinus histiocytosis with massive lymphadenopathy is a benign pseudolymphomatous disease with distinctive microscopic features. Painless cervical adenopathy is the most characteristic clinical finding, although other node groups and extranodal sites may be involved. Of 200 patients in a case registry, 8 had neurologic symptoms. The lesions included vertebral canal and intracranial infiltrates and a destructive vertebral body lesion. Two patients had both cord compression and intracranial disease; one of them died after 10 years of disease. Seven patients were alive 1 to 15 years after disease onset.
伴巨大淋巴结病的窦性组织细胞增生症是一种具有独特显微镜下特征的良性假淋巴瘤性疾病。无痛性颈部淋巴结病是最具特征性的临床发现，尽管其他淋巴结组和结外部位也可能受累。在一个病例登记中的200例患者中，8例有神经系统症状。病变包括椎管和颅内浸润以及椎体破坏性病变。2例患者既有脊髓受压又有颅内疾病；其中1例在患病10年后死亡。7例患者在疾病发作后1至15年仍存活。
