Jones D B, Smith P M
Br J Ind Med. 1982 Aug;39(3):306-7. doi: 10.1136/oem.39.3.306.
ABSTRACT Two vinyl chloride monomer (VCM) workers, who developed non-cirrhotic portal fibrosis and portal hypertension, died from angiosarcoma of the liver five and ten years later respectively, despite withdrawal from occupational exposure. We suggest that non-cirrhotic portal fibrosis caused by exposure to VCM is potentially premalignant and that those workers who already have the condition should be carefully monitored.
摘要 两名氯乙烯单体(VCM)工人患上了非肝硬化性门脉纤维化和门脉高压症,尽管他们已不再接触职业性暴露因素,但分别在5年后和10年后死于肝血管肉瘤。我们认为,接触VCM所致的非肝硬化性门脉纤维化有潜在的恶变可能,应对已有此病症的工人进行密切监测。