Mayberry J F, Dew M J, Morris J S
Postgrad Med J. 1982 Feb;58(676):112-4. doi: 10.1136/pgmj.58.676.112.
Monozygous twin sisters developed ulcerative colitis within 7 years of each other. Both had distal colitis confirmed by histology and radiology. Their maternal grandmother subsequently developed the disease. The long interval between the onset of the disease in the twins suggests a role for environmental factors in addition to genetic influences. Although about five hundred sets of twins with ulcerative colitis may be expected in Britain, this is the first set to be reported.
单卵双胞胎姐妹在彼此7年之内都患上了溃疡性结肠炎。两人均经组织学和放射学确诊为远端结肠炎。她们的外祖母随后也患上了这种疾病。双胞胎发病间隔时间较长，这表明除了遗传影响外，环境因素也起了作用。虽然在英国预计可能有大约500对患有溃疡性结肠炎的双胞胎，但这是第一对被报道的。
