Albert D J, Walsh M L
Physiol Behav. 1982 May;28(5):791-5. doi: 10.1016/0031-9384(82)90195-0.
In rats subjected to lesions of the medial hypothalamus, 8 of 11 animals became mouse killers and all manifested some degree of hyperreactivity to the experimenter. When introduced as intruders into a mixed sex colony group, the lesioned rats did not manifest piloerection nor did they emit flank attacks characteristic of social aggressive behavior. However, the lesioned animals did respond to the attacks of the resident male rats with significantly more counterattacks and biting than did sham-lesioned control rats. Spontaneous mouse killing rats also failed to show a level of social aggressive behavior significantly greater than that of sham-operated control rats, but the spontaneous mouse killers did kill rat pups in the colony groups. Alpha-male rats when introduced as an intruder into a colony group did exhibit piloerection and emit flank attacks characteristic of social aggressive behavior. These results demonstrate that the mouse killing and heightened reactivity associated with medial hypothalamic lesions do not represent an indiscriminant release of all forms of agonistic behavior.
在接受内侧下丘脑损伤的大鼠中，11只动物中有8只变成了杀鼠者，并且所有动物对实验者都表现出一定程度的过度反应。当作为入侵者引入到一个混合性别的群体中时，损伤的大鼠既没有出现竖毛现象，也没有发出具有社会攻击性行为特征的胁腹攻击。然而，与假手术对照组大鼠相比，损伤的动物对常驻雄性大鼠的攻击做出的反击和撕咬明显更多。自发杀鼠的大鼠也没有表现出比假手术对照组大鼠明显更高水平的社会攻击性行为，但是自发杀鼠者确实会杀死群体中的幼鼠。当将优势雄性大鼠作为入侵者引入群体时，它们确实会出现竖毛现象，并发出具有社会攻击性行为特征的胁腹攻击。这些结果表明，与内侧下丘脑损伤相关的杀鼠行为和反应性增强并不代表所有形式的攻击性行为的无差别释放。
