中枢给予酪氨酸的降压作用。
The hypotensive effect of centrally administered tyrosine.
作者信息
Yamori Y, Fujiwara M, Horie R, Lovenberg W
出版信息
Eur J Pharmacol. 1980 Nov 21;68(2):201-4. doi: 10.1016/0014-2999(80)90323-4.
PMID:7202487
Abstract
Intraventricular injection of 15 microgram L-tyrosine results in a significant reduction in blood pressure in the spontaneously hypertensive rat. An increase in the turnover of norepinephrine as indexed by MOPEG-SO4 is observed concurrently. The data are consistent with the previously suggested depressor role of certain central noradrenergic neurons.
摘要
向自发性高血压大鼠脑室内注射15微克L-酪氨酸可导致血压显著降低。同时观察到以MOPEG-SO4为指标的去甲肾上腺素周转率增加。这些数据与先前提出的某些中枢去甲肾上腺素能神经元的降压作用一致。
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