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大鼠肝脏、肾脏和大脑中的甲状腺激素与组织蛋白酶D活性

Thyroid hormones and cathepsin D activity in the rat liver, kidney and brain.

作者信息

Satav J G, Katyare S S

出版信息

Experientia. 1981 Jan 15;37(1):100-2. doi: 10.1007/BF01965594.

Abstract

The effect of thyroidectomy and subsequent treatment with tri-iodothyronine (T3), as well as that of thyrotoxicosis, was examined on cathepsin D activity in the rat liver, kidney and brain. Thyrotoxicosis resulted in a generalized increase in the enzyme activity in the 3 tissues; the effect of other thyroidal states was diverse and tissue-specific.

摘要

研究了甲状腺切除术及随后用三碘甲状腺原氨酸(T3)治疗的效果,以及甲状腺毒症对大鼠肝脏、肾脏和大脑中组织蛋白酶D活性的影响。甲状腺毒症导致这3种组织中的酶活性普遍升高;其他甲状腺状态的影响则各不相同且具有组织特异性。

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