Bennell M A, Husband A J
Immunology. 1981 Mar;42(3):469-74.
Evidence is presented which indicates that recirculating lymphocytes originating from the intestine in pigs are returned to the blood circulation at the level of the mesenteric lymph nodes (MLN) and not via efferent intestinal lymph. This was demonstrated by three observations: (1) removal of all MLN resulted in a thirty-fold increase in lymphocyte numbers in efferent lymph of pigs, but not in rats; (2) there are about twenty-five times more lymphocytes in afferent intestinal lymph than efferent intestinal lymph in normal pigs; (3) 51Cr-labelled lymphocytes injected into afferent lymphatics are mostly recovered in the node tissue or efferent lymph of sheep, and very few in the venous drainage, whereas in pigs relatively few labelled cells are recovered in the node or in efferent lymph.
有证据表明，猪体内源自肠道的再循环淋巴细胞是在肠系膜淋巴结（MLN）水平返回血液循环的，而非通过肠输出淋巴管。这一现象通过三项观察得以证实：（1）切除所有MLN会使猪的输出淋巴管中淋巴细胞数量增加30倍，但对大鼠则无此影响；（2）正常猪的肠输入淋巴管中的淋巴细胞数量比肠输出淋巴管中的淋巴细胞数量多约25倍；（3）注入输入淋巴管的51Cr标记淋巴细胞大多在绵羊的淋巴结组织或输出淋巴管中回收，很少在静脉引流中回收，而在猪中，在淋巴结或输出淋巴管中回收的标记细胞相对较少。
