Düchting W, Dehl G
Int J Biomed Comput. 1980 May;11(3):175-95. doi: 10.1016/0020-7101(80)90044-6.
Continuing previous studies in which tumor diseases were interpreted as unstable control loops, the present paper tries to determine the spatial structure and the time behaviour of cell renewal systems. For this purpose a computer model for the two-dimensional cell space was developed, which is described by a set of specifications and growth statements. Selected case studies are then simulated by means of a digital computer (CYBER 76). The development of this model enables a deeper insight into the structure and function of disturbed cell renewal processes. Furthermore, it is possible with this computer model to simulate simple basic cases which, in reality, could hardly or not at all be tested.
延续先前将肿瘤疾病解释为不稳定控制回路的研究，本文试图确定细胞更新系统的空间结构和时间行为。为此，开发了一个二维细胞空间的计算机模型，该模型由一组规范和生长语句描述。然后通过数字计算机（CYBER 76）对选定的案例研究进行模拟。该模型的开发有助于更深入地了解受干扰的细胞更新过程的结构和功能。此外，利用这个计算机模型可以模拟一些在现实中几乎无法或根本无法测试的简单基本情况。
