Steinberg R H, Niemeyer G
Invest Ophthalmol Vis Sci. 1981 Mar;20(3):415-8.
We have inquired whether a change in [K+]0 is associated in time with the light peak of the DC electroretinogram (ERG). If it is, this would implicate a change in [K+]0 as participating in the generation of the light peak. (The same response is usually recorded in humans by the the indirect technique of electro-oculography, giving the electro-oculogram (EOG).) Changes in [K+]0 were recorded with double-barrel, K+-specific microelectrodes from the retina and vitreous of the dark-adapted intact cat eye in response to maintained illumination. The light peak of the DC ERG was recorded from the reference barrel of the microelectrode when it was placed in the vitreous. No correlation was observed between the light peak and the changes in [K+]0 that were recorded in the retina or vitreous. We conclude that a retinal or vitreal change in [K+]0 is not directly involved in the mechanism that generates the light peak of the DC ERG.
我们已经探究了细胞外钾离子浓度（[K+]0）的变化是否与直流视网膜电图（ERG）的光峰在时间上相关联。如果是这样，这将意味着[K+]0的变化参与了光峰的产生。（在人类中，通常通过间接的眼电图技术记录到相同的反应，即产生眼电图（EOG）。）使用双管钾离子特异性微电极，记录了暗适应的完整猫眼视网膜和玻璃体中[K+]0的变化，以响应持续光照。当微电极的参考管置于玻璃体中时，从该参考管记录直流ERG的光峰。在视网膜或玻璃体中记录到的[K+]0变化与光峰之间未观察到相关性。我们得出结论，视网膜或玻璃体中[K+]0的变化不直接参与产生直流ERG光峰的机制。
