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水溶性造影剂用于脊髓造影和气脑造影的早期及晚期副作用:简要综述

Early and late side effects of water-soluble contrast media for myelography and cisternography: a short review.

作者信息

Ahlgren P

出版信息

Invest Radiol. 1980 Nov-Dec;15(6 Suppl):S264-6. doi: 10.1097/00004424-198011001-00056.

Abstract

Acute and chronic neurotoxicities of the ionic contrast media Conray, Dimer X, Dimer X and a steroid, and a nonionic contrast medium metrizamide (Amipaque) are reviewed. All ionic media induced late arachnoiditis potentiated by intrathecal steroids. Amipaque did not induce late arachnoiditis, but it produced a number of acute side effects. Myelography in patients given a phenothiazine (levomepromazine) was associated with a decreased incidence of side effects compared with a nonmedicated group.

摘要

本文综述了离子型造影剂Conray、Dimer X、Dimer X以及一种类固醇和非离子型造影剂甲泛葡胺(阿米培克)的急慢性神经毒性。所有离子型造影剂均可诱发迟发性蛛网膜炎,鞘内注射类固醇会加重这种情况。甲泛葡胺不会诱发迟发性蛛网膜炎,但会产生一些急性副作用。与未用药组相比,接受吩噻嗪类药物(左美丙嗪)治疗的患者进行脊髓造影时副作用发生率降低。

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