迟发性皮肤卟啉症合并威尔逊氏病

Porphyria cutanea tarda complicating Wilson's disease.

作者信息

Chesney T M, Wardlaw L L, Kaplan R J, Chow J F

出版信息

J Am Acad Dermatol. 1981 Jan;4(1):64-6. doi: 10.1016/s0190-9622(81)70010-0.

PMID:7204691

Abstract

A young woman is described in whom symptomatic porphyria cutanea tarda (PCT) developed during copper chelation therapy for Wilson's disease. Termination of ethanol ingestion and oral contraceptive use resulted in cessation of blistering skin lesions and reduction in urinary porphyrin excretion. This is the first recorded coincidence of these two rare hepatic diseases. Therapeutic implications are discussed.

摘要

本文描述了一名年轻女性，她在接受威尔逊病的铜螯合治疗期间出现了症状性迟发性皮肤卟啉症（PCT）。停止摄入乙醇和使用口服避孕药后，皮肤水疱性病变停止，尿卟啉排泄减少。这是这两种罕见肝病首次同时出现的记录。文中讨论了其治疗意义。