Inhibiting effect of non-steroidal anti-inflammatory drugs on the chemotaxis of human leukocytes in vitro.

Chemotaxis of human leukocytes was inhibited in vitro by four non-steroidal anti-inflammatory drugs, namely, lysine acetylsalicylate, phenylbutazone, indomethacin, and indoprofen. Dose-dependent effects were always found and significant regression was proved for all drugs except phenylbutazone.