Brodal A, Walberg F
J Comp Neurol. 1977 Nov 15;176(2):281-94. doi: 10.1002/cne.901760209.
Microinjections (30-50 nl) of a horseradish peroxidase (HRP) suspension of 25% (wt./vol.) were made in different folia of the paramedian lobule of cats, and the sites of occurrence of labeled cells in the inferior olive were precisely determined. In each case only a small number of cells are labeled, aggregated in a minute area. The labeled cells are found within three only of the four olivary areas previously determined (Brodal et al., '75) to project onto the paramedian lobule (fig. 1): one area in the rostral half of the medial accessory olive, another in the dorsal accessory olive (except its caudalmost part), and a third in part of the caudal half of the dorsal lamella of the principal olive. Labeled cells were never found in the fourth area, the ventral lamella. A distinct zonal pattern in the projection is demonstrated (figs. 3, 5B): a middle longitudinal zone of the paramedian lobule receives olivary afferents from the area in the medial accessory olive, a medial zone from part of the projection area in the dorsal accessory olive, a lateral zone from part of the projection area in the dorsal lamella. This zonal projection appears to extend throughout the length of the paramedian lobule (the two caudalmost folia could not be studied). tthe somatotopical pattern in the projections from the accessory olives described previously (Brodal et al., '75) is confirmed. The pattern of a zonal projection obtained with the HRP-method (fig 5B) is simpler than that deduced by Armstrong et al ('74) from recordings of antidromic potentials in the olive (fig 5A). Concerning main points there is satisfactory agreement. The phenomenon that following microinjections of HRP in superficial parts of the folia labeled cells occur within parts only of the regions of the olive which contain labeled cells following large HRP-injections in the paramedian lobule is discussed.
将25%（重量/体积）的辣根过氧化物酶（HRP）悬浮液以30 - 50纳升的量微量注射到猫正中旁小叶的不同小叶中，并精确确定下橄榄核中标记细胞的出现位置。在每种情况下，只有少数细胞被标记，聚集在一个微小区域内。标记细胞仅在先前确定的（布罗达尔等人，1975年）投射到正中旁小叶的四个橄榄核区域中的三个区域内被发现（图1）：一个区域在内侧副橄榄核的前半部分，另一个在背侧副橄榄核（除其最尾端部分），第三个在主橄榄核背侧薄片后半部分的一部分。在第四个区域，即腹侧薄片中从未发现标记细胞。投射中呈现出明显的带状模式（图3、5B）：正中旁小叶的中间纵向带接收来自内侧副橄榄核区域的橄榄核传入纤维，内侧带接收来自背侧副橄榄核投射区域一部分的传入纤维，外侧带接收来自背侧薄片投射区域一部分的传入纤维。这种带状投射似乎贯穿正中旁小叶的全长（最尾端的两个小叶未进行研究）。先前描述的（布罗达尔等人，1975年）副橄榄核投射中的躯体定位模式得到了证实。用HRP方法获得的带状投射模式（图5B）比阿姆斯特朗等人（1974年）从橄榄核中逆行电位记录推导出来的模式（图5A）更简单。在主要要点方面存在令人满意的一致性。讨论了在小叶浅层微量注射HRP后，标记细胞仅出现在正中旁小叶大量注射HRP后橄榄核中含有标记细胞区域的部分区域内的现象。
