Pasich J, Niedworok E, Warzecha U
Pharmazie. 1980 Dec;35(12):777.
The liberation of glaucine hydrobromide from Tussiglauzin dragées has been verified. The release to artificial gastric juice was determined by three different procedures: method using the apparatus according to Grzesiczak, stationary-basket method and rotating-basket method. All three methods showed that the largest proportion of the drug (greater than 90%) is released within 2.5 h, the maximum amount determined by means of the rotating-basket method being 99.2%.
已证实从吐根糖浆糖衣丸中释放出氢溴酸格劳君。通过三种不同程序测定其在人工胃液中的释放情况:使用Grzesiczak装置的方法、固定篮法和旋转篮法。所有这三种方法均表明,最大比例的药物(超过90%)在2.5小时内释放,通过旋转篮法测定的最大释放量为99.2%。