Dallmeier K, Carlini E A
Pharmacology. 1981;22(2):113-27. doi: 10.1159/000137479.
Nine newly synthesized eugenol derivatives were investigated in rats or mice as to their anesthetic, hypothermic, myorelaxant and anticonvulsant effects. Additional pharmacological activity which appeared during the experiments is described. For comparative purposes, six naturally occurring eugenol analogues were included in the study. The results are further discussed as to possible structure-activity relationships between the test compounds and the four investigated effects.
对九种新合成的丁香酚衍生物在大鼠或小鼠身上进行了麻醉、降温、肌松和抗惊厥作用的研究。描述了实验过程中出现的其他药理活性。为作比较，该研究纳入了六种天然存在的丁香酚类似物。进一步讨论了测试化合物与四种研究效应之间可能的构效关系。
