Krieger J, Mangin P, Kurtz D
Rev Electroencephalogr Neurophysiol Clin. 1980 Apr-Jun;10(2):177-85. doi: 10.1016/s0370-4475(80)80051-7.
The authors studied sleep organization and modifications in ventilation in 20 healthy subjects (11 men, 9 women) with an average age of 65 years. There was a diminution (in relation to young adults) in the quantity of sleep with a relative increase in light slow wave sleep and reduction in deep slow wave and REM sleep phases. A reduction was also noted in the ventilation rate during slow wave and REM sleep phases in relation to calm awake periods, especially towards the end of the night. This was due to a reduction in tidal volume insufficiently compensated by an increased ventilation frequency. Hypopnea and apnea were noted in 19 of the 20 subjects, the latter occurring in the form of obstructive apnea during light slow wave sleep. The variable number of apnea can be used to divide the subjects into two sub-groups: one group of 14 of the subjects who had less than 50 apnea; the other group containing 6 subjects, all males, having more than 80 apnea during the night, and being identical to a group of patients with the sleep apnea syndrome.
作者对20名平均年龄为65岁的健康受试者（11名男性，9名女性）的睡眠结构和通气变化进行了研究。与年轻人相比，睡眠量减少，浅慢波睡眠相对增加，深慢波睡眠和快速眼动睡眠阶段减少。与安静清醒期相比，慢波睡眠和快速眼动睡眠阶段的通气率也降低，尤其是在夜间快结束时。这是由于潮气量减少，而通气频率增加不足以补偿。20名受试者中有19名出现呼吸浅慢和呼吸暂停，后者以浅慢波睡眠期间的阻塞性呼吸暂停形式出现。呼吸暂停的数量不同可将受试者分为两个亚组：一组14名受试者呼吸暂停少于50次；另一组有6名受试者，均为男性，夜间呼吸暂停超过80次，与一组睡眠呼吸暂停综合征患者相同。
