Barr R D, Davidson A R, Jung L K, Mohan Pai K R
Scand J Haematol. 1980 Oct;25(4):363-8.
Increased osmotic fragility and methaemoglobin generation in vitro have resulted from the exposure of normal human erythrocytes to numerous cancer chemotherapeutic agents. These findings offer a possible explanation for the earlier, consistent clinical observation of the rapid development of anaemia, during consolidation therapy, in children with acute lymphoblastic leukaemia in remission.
正常人红细胞暴露于多种癌症化疗药物后，在体外出现渗透脆性增加和高铁血红蛋白生成。这些发现为缓解期急性淋巴细胞白血病患儿在巩固治疗期间贫血迅速发展这一较早出现的、一致的临床观察结果提供了一种可能的解释。
