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非洲猪瘟病毒西半球分离株:无症状携带者及对攻毒接种的抗性

Western hemisphere isolates of African swine fever virus: asymptomatic carriers and resistance to challenge inoculation.

作者信息

Mebus C A, Dardiri A H

出版信息

Am J Vet Res. 1980 Nov;41(11):1867-9.

PMID:7212418
Abstract

Convalescent clinically normal pigs were tested for the persistence of African swine fever (ASF) infection. One group of pigs was examined 135 days after inoculation with a Brazilian isolate and a 2nd group was examined 110 days after inoculation with a Dominican Republic isolate. Susceptible pigs exposed by contact to these groups remained clinically normal. These contact pigs plus 2 more pigs added to each group developed ASF after being fed and inoculated with tissues collected from recovered pigs. African swine fever virus was not isolated in swine buffy coat cultures inoculated with supernatant fluid from the collected tissues. The remaining convalescent Brazilian and Dominican Republic ASF pigs were challenge inoculated with homologous virus and then with Lisbon 60 ASF virus. Pigs in both groups remained clinically normal after homologous virus challenge inoculation. Pigs in the Brazilian group remained clinically normal after inoculation of the lisbon 60 ASF viral isolate. Of 5 pigs in the Dominican Republic group, 3 developed a transient viremia after inoculation of the Lisbon 60 ASF viral isolate.

摘要

对临床康复的正常猪进行了非洲猪瘟(ASF)感染持续性检测。一组猪在接种巴西分离株135天后接受检查,另一组猪在接种多米尼加共和国分离株110天后接受检查。通过接触暴露于这些组的易感猪仍保持临床正常。这些接触猪加上每组额外添加的2头猪,在喂食并接种从康复猪采集的组织后患上了ASF。用采集组织的上清液接种猪血沉棕黄层培养物,未分离出非洲猪瘟病毒。其余康复的巴西和多米尼加共和国ASF猪先用同源病毒进行攻击接种,然后用里斯本60 ASF病毒进行接种。两组猪在同源病毒攻击接种后均保持临床正常。巴西组的猪在接种里斯本60 ASF病毒分离株后仍保持临床正常。在多米尼加共和国组的5头猪中,3头在接种里斯本60 ASF病毒分离株后出现了短暂的病毒血症。

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Western hemisphere isolates of African swine fever virus: asymptomatic carriers and resistance to challenge inoculation.非洲猪瘟病毒西半球分离株:无症状携带者及对攻毒接种的抗性
Am J Vet Res. 1980 Nov;41(11):1867-9.
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