Broughton W L, Fine B S, Zimmerman L E
Arch Ophthalmol. 1981 Mar;99(3):481-6. doi: 10.1001/archopht.1981.03930010483021.
A pair of eyes with congenital glaucoma, one treated by goniotomy, was examined by light and electron microscopy. Examination of the drainage angles afforded the opportunity to compare anatomic changes in the treated eye with the surgically unaltered tissue of the fellow eye. The congenital glaucoma appeared to arise from compression of the trabecular meshwork and closure of the intertrabecular and transtrabecular spaces by a discontinuous "membrane" consisting of ectopic trabecular pillars that bridged the drainage angle from the iris root to the normally positioned uveal meshwork. Cleavage of trabecular pillars during goniotomy and conversion of angle architecture to that of a nonglaucomatous neonatal eye suggest that aberrant or ectopic trabecular pillars acted mechanically in maintaining angle compression. The uveal and corneoscleral meshwork and Schlemm's canal are present and appear normal.
对一只患有先天性青光眼且经前房角切开术治疗的眼睛进行了光镜和电镜检查。对房角的检查提供了一个机会，可将治疗眼的解剖学变化与对侧未手术眼的组织进行比较。先天性青光眼似乎是由于小梁网受压以及由异位小梁柱组成的不连续“膜”封闭了小梁间和小梁间通道所致，这些小梁柱从虹膜根部跨越房角连接到正常位置的葡萄膜小梁网。前房角切开术中小梁柱的分离以及房角结构转变为非青光眼新生儿眼的结构，提示异常或异位的小梁柱在维持房角受压方面起机械作用。葡萄膜和角膜巩膜小梁网以及施莱姆管均存在且外观正常。
