[Morphology of the induction process during following bone matrix implantation in mice].

A decalcified bone matrix was implanted intramuscularly to normal mice, to mice irradiated by 450 R, to mice with curretaged femur and beneath the renal capsule in normal mice. In the course of implantation the bone induction was noted in 80% of cases. In all the series of experiments, the implants had different degrees of maturity of induced bone tissue and different extent of repopulation of the induced bone by hemopoietic cells. Hemopoietic cells inhabited young osteogenic tissue with a well marked osteoblastic layer and formed bone marrow cavity. No hemopoiesis was observed in the case of induction of cavity-free bone tissue plates or mature bones with bone marrow cavity but without osteoblastic layer.