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Transient leukemoid proliferation of the cytogenetically unbalanced +21 cell line of a constitutional mosaic boy.

作者信息

Heaton D C, Fitzgerald P H, Fraser G J, Abbott G D

出版信息

Blood. 1981 May;57(5):883-7.

PMID:7214018
Abstract

A newborn without any signs of Down's syndrome was found to have an acute proliferation that remitted without drug therapy. Chromosomal analysis of blood, bone marrow, and skin cells revealed that the child was a constitutional mosaic with normal cells and a low number of cells in which one no. 21 chromosome was replaced by a probably isochromosome for the no. 21 long arm: 46,XY/46,XY,i(21q). The abnormal cell line of the mosaic appeared to be selectively involved in this proliferation.

摘要

相似文献

1
Transient leukemoid proliferation of the cytogenetically unbalanced +21 cell line of a constitutional mosaic boy.
Blood. 1981 May;57(5):883-7.
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A case of acute myeloblastic leukemia with chromosomes showing 46, XY = 11/46, XY, 21q- = 39.一例急性髓细胞白血病患者，其染色体显示为46，XY = 11/46，XY，21q- = 39。
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[Juvenile type of chronic myelogenous leukemia in a 3 6/12 year old boy with trisomy 21 mosaicism but no symptoms of Down's syndrome (author's transl)].一名3岁6个月大患有21号染色体三体嵌合体但无唐氏综合征症状的男孩患青少年型慢性粒细胞白血病（作者译）
Monatsschr Kinderheilkd (1902). 1977 Jul;125(7):740-3.

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