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减少铝暴露:一种可能与膀胱癌相关的职业。

Reducing aluminum: an occupation possibly associated with bladder cancer.

作者信息

Thériault G, De Guire L, Cordier S

出版信息

Can Med Assoc J. 1981 Feb 15;124(4):419-22, 425.

Abstract

A case-control study, undertaken to identify reasons for the exceptionally high incidence of bladder cancer among men in the Chicoutimi census division of the province of Quebec, revealed an increased risk associated with employment in the electrolysis department of an aluminum reduction plant. The estimated relative risk was 2.83 (95% confidence interval; 1.06 to 7.54). An interaction was found between such employment and cigarette smoking, resulting in a combined relative risk of 5.70 (95% confidence interval: 2.00 to 12.30). These findings suggest that employment in an aluminum reduction plant accounts for part of the excess of bladder cancer in the region studied.

摘要

一项病例对照研究旨在确定魁北克省奇库蒂米普查区男性膀胱癌发病率异常高的原因,该研究发现,在一家铝冶炼厂的电解部门工作会增加患癌风险。估计相对风险为2.83(95%置信区间:1.06至7.54)。研究发现,这种工作与吸烟之间存在相互作用,综合相对风险为5.70(95%置信区间:2.00至12.30)。这些发现表明,在铝冶炼厂工作是该研究区域膀胱癌高发的部分原因。

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本文引用的文献

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BLADDER TUMOURS IN THE ELECTRIC-CABLE INDUSTRY.
Lancet. 1965 Jul 24;2(7404):143-6. doi: 10.1016/s0140-6736(65)90228-x.
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The association of smoking with cancer of the urinary bladder in humans.
AMA Arch Intern Med. 1956 Aug;98(2):129-35. doi: 10.1001/archinte.1956.00250260001001.
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Smoking and cancer of the lower urinary tract.吸烟与下尿路癌症
N Engl J Med. 1971 Jan 21;284(3):129-34. doi: 10.1056/NEJM197101212840304.
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Bladder tumors in rats fed cyclohexylamine or high doses of a mixture of cyclamate and saccharin.
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