Benveniste J
Clin Allergy. 1981 Jan;11(1):1-11. doi: 10.1111/j.1365-2222.1981.tb01559.x.
We have designed a human basophil degranulation test based on a one-step method of basophil staining after exposure to a specific allergen. This very simple test is now commercially available as a ready-to-use kit. It explores the allergic sensitivity at the cellular level, probably through IgE-dependent sensitization of the basophil. It positively correlates with histamine release and radioallergosorbent test (RAST). It detects sensitivity to common allergens and to chemical and food products as well. In its present state, the test provides a simple, inexpensive specific means for in vitro diagnosis of allergic diseases. Recently, it has been further developed to be performed on the automatic Hemalog D Technicon machine.
我们设计了一种人类嗜碱性粒细胞脱颗粒试验，该试验基于暴露于特定过敏原后嗜碱性粒细胞染色的一步法。这个非常简单的试验现在作为即用型试剂盒在市场上有售。它可能通过嗜碱性粒细胞的IgE依赖性致敏作用，在细胞水平上探究过敏敏感性。它与组胺释放和放射变应原吸附试验（RAST）呈正相关。它还能检测对常见过敏原以及化学和食品的敏感性。就目前的状态而言，该试验为过敏性疾病的体外诊断提供了一种简单、廉价的特异性方法。最近，它已进一步发展为可在自动血细胞分析仪Hemalog D Technicon上进行。
