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[在创伤后骨髓炎、骨关节炎和软组织感染的治疗中使用庆大霉素-聚甲基丙烯酸甲酯链有哪些优势?]

[What advantage are there in using gentamycin-PMMA-chains in the treatment of posttraumatic osteomyelitis, osteoarthritis and soft tissue infections?].

作者信息

Eberle H

出版信息

Helv Chir Acta. 1978 Dec;45(4-5):603-7.

PMID:721603
Abstract

The use of gentamicin-polymethylmethacrylate (PMMA) bead chains permits the depositing of a high dose of gentamicin at the place of the infection. Short indications on the experimental basis and hints regarding the practical application are given. It follows the discussion of the results in 34 patients with chronic posttraumatic osteomyelitis, arthritis due to infection, diabetic and arteriosclerotic gangrene and the infections of the soft tissues. Primary wound healing was achieved in 70%. Discussion of interesting cases. The advantages of the use of gentamicin-PMMA bead chains in infection cases are emphasized.

摘要

庆大霉素-聚甲基丙烯酸甲酯(PMMA)珠链的应用可在感染部位高剂量使用庆大霉素。本文给出了基于实验的简要适应证及实际应用的提示。随后讨论了34例慢性创伤后骨髓炎、感染性关节炎、糖尿病和动脉硬化性坏疽以及软组织感染患者的治疗结果。70%的患者实现了一期伤口愈合。文中还讨论了一些有趣的病例。强调了在感染病例中使用庆大霉素-PMMA珠链的优势。

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