Averdunk R, Grüner J
J Clin Chem Clin Biochem. 1981 Feb;19(2):89-97.
All reagents for determination of thromboplastin time (Quick-test) tested so far are sensitive to non-carboxylated clotting factor X, and sensitivity varies, depending on the reagent. The thromboplastins of Behring and Thrombotest are very sensitive. The preparations of La-Roche and Boehringer are somewhat more sensitive than those of Dade and Goedecke. Only the differences between the first group (Behring, Thrombotest) and the others are significant. There is a good correlation between factor X sensitivity, prothrombin time and non-carboxylated clotting factor X sensitivity, with all reagents. These results may be of significance for quality control and standardization of the prothrombin time.
迄今为止所测试的所有用于测定凝血活酶时间（Quick 试验）的试剂，对未羧化的凝血因子 X 均敏感，且敏感性因试剂而异。拜耳和血栓试验的凝血活酶非常敏感。罗氏和勃林格的制剂比达德和戈德克的制剂稍敏感一些。只有第一组（拜耳、血栓试验）与其他组之间的差异具有显著性。对于所有试剂而言，因子 X 敏感性、凝血酶原时间和未羧化凝血因子 X 敏感性之间存在良好的相关性。这些结果可能对凝血酶原时间的质量控制和标准化具有重要意义。
