Ulsamer A G, Porter W K, Osterberg R E
J Environ Pathol Toxicol. 1978 May-Jun;1(5):543-9.
Surface tris-(2,3-dibromopropyl) phosphate (TRIS) was removed from flame-retarded polyester fabric by benzene-hexane extraction and replaced with 14C-TRIS. Sections of the radiolabeled fabric (10 X 12 cm) were placed in contact with the clipped skins of rabbits, and urine and feces were collected over a 96 hr period. The cloths were allowed to remain dry or were moistened with either urine or simulated sweat. A similar collection of urine and feces was performed following i.v. injection of 14C-TRIS. From the results of these experiments, it can be calculated that up to 17 percent of the radiolabel on the cloth penetrated rabbit skin over the 96 hr period of exposure. Most of the excreted radiolabel appeared in the urine, with the kidney being the organ of highest specific radioactivity. The highest absorption of radiolabel occurred in the urine-moistened cloth group. Moistening the cloth with simulated sweat produced no increase in absorption over that seen with dry cloth.
通过苯 - 己烷萃取从阻燃聚酯织物上去除表面的磷酸三（2,3 - 二溴丙基）酯（TRIS），并用14C - TRIS进行替换。将放射性标记的织物切片（10×12厘米）与兔子的剪毛皮肤接触，并在96小时内收集尿液和粪便。使布料保持干燥，或者用尿液或模拟汗液润湿。静脉注射14C - TRIS后，进行类似的尿液和粪便收集。根据这些实验结果，可以计算出在96小时的暴露期间，布料上高达17%的放射性标记穿透了兔子皮肤。大部分排泄出的放射性标记出现在尿液中，肾脏是比放射性最高的器官。放射性标记的最高吸收发生在尿液润湿的布料组中。用模拟汗液润湿布料，其吸收量相比干燥布料没有增加。
