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儿童会从睡衣中吸收三(2-氯丙基)磷酸酯阻燃剂:尿液中含有致突变代谢物2,3-二溴丙醇。

Children absorb tris-BP flame retardant from sleepwear: urine contains the mutagenic metabolite, 2,3-dibromopropanol.

作者信息

Blum A, Gold M D, Ames B N, Jones F R, Hett E A, Dougherty R C, Horning E C, Dzidic I, Carroll D I, Stillwell R N, Thenot J P

出版信息

Science. 1978 Sep 15;201(4360):1020-3. doi: 10.1126/science.684422.

Abstract

The flame retardant, tris(2,3-dibromopropyl)phosphate (tris-BP), which is a mutagen and causes cancer and sterility in animals is absorbed from fabric by people. 2,3-Dibromopropanol, a metboloite of tris-BP and a mutagen itself, has been found in the urine samples of ten children who were wearing or who had worn tris-BP-treated sleepwear. Eight of these children were wearing well-washed sleepwear and the possibility of absorption of tris-BP from well-washed sleepwear discussed. 2,3-Dibromopropanol was not found in the urines of one child and one adult who had never worn tris-BP-treated garments.

摘要

阻燃剂磷酸三(2,3 - 二溴丙基)酯(Tris - BP)是一种诱变剂,可导致动物患癌症和不育,人们会从织物中吸收这种物质。2,3 - 二溴丙醇是Tris - BP的一种代谢产物,其本身也是一种诱变剂,在10名穿着或曾穿着经Tris - BP处理的睡衣的儿童的尿液样本中被发现。其中8名儿童穿着洗得很干净的睡衣,探讨了从洗得很干净的睡衣中吸收Tris - BP的可能性。在一名从未穿过经Tris - BP处理的衣物的儿童和一名成年人的尿液中未发现2,3 - 二溴丙醇。

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