Peetz M E, Awrich A E, Moseley H S, Keenan E J, Davenport C E, Fletcher W S
Am J Surg. 1981 May;141(5):554-8. doi: 10.1016/0002-9610(81)90047-7.
The records of 204 women with metastatic breast carcinoma treated by oophorectomy were analyzed. Premenopausal women had a response rate of 50 percent. Forty-one percent of postmenopausal women responded. Those who responded had an average duration of response of 22 months and a length of survival twice that of the nonresponders. There was a better than 60 percent correlation between response to oophorectomy and response to further endocrine ablation. Response to endocrine manipulation is more a function of the hormonal sensitivity of the carcinoma than of menopausal status.
对204例接受卵巢切除术治疗的转移性乳腺癌女性患者的记录进行了分析。绝经前女性的缓解率为50%。绝经后女性的缓解率为41%。有反应者的平均缓解持续时间为22个月，生存期是非反应者的两倍。卵巢切除术反应与进一步内分泌消融反应之间的相关性超过60%。内分泌治疗反应更多地取决于癌的激素敏感性，而非绝经状态。
