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[脑苷脂和鞘磷脂双层膜的离子通透性]

[Ion permeability of cerebroside and sphingomyelin bilayer membranes].

作者信息

Mkheian E E, Sotskiĭ O P, Akopov S E, Badzhinian S A

出版信息

Biofizika. 1981 Jan-Feb;26(1):137-8.

PMID:7225441
Abstract

Ionic conductivity of bilayer membranes formed of cerebrosides and sphingomeylins isolated from bovine brains and its dependence on medium pH were studied. It was found that conductivity of the membranes from cerebrosides in KC1, CaCl2 solutions is 2-3 orders, and from sphingomyelin 1-2 orders higher than that of bilayers from lecithin and phospholipids. Both in cerebroside and sphingomyelin membranes the conductivity depended on medium pH, unlike the bilayer membranes of the brain and liver phospholipids.

摘要

研究了从牛脑中分离出的脑苷脂和鞘磷脂形成的双层膜的离子电导率及其对介质pH值的依赖性。结果发现,脑苷脂双层膜在氯化钾、氯化钙溶液中的电导率比卵磷脂和磷脂双层膜高2 - 3个数量级,鞘磷脂双层膜则高1 - 2个数量级。与脑和肝磷脂双层膜不同,脑苷脂和鞘磷脂双层膜的电导率均依赖于介质pH值。

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