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人类中苯丙胺诱导行为的灵长类动物类似物。

A primate analogue of amphetamine-induced behaviors in humans.

作者信息

Haber S, Barchas P R, Barchas J D

出版信息

Biol Psychiatry. 1981 Feb;16(2):181-96.

PMID:7225485
Abstract

The effects of amphetamine on individual and social behaviors were studied in two colonies of rhesus monkeys. After an initial base-line period, each animal, in turn, received low chronic drug administration for 3 weeks. Between each drug period new base-line data were collected. During amphetamine administration, there was a significant increase in the following behaviors: time spent in "sit tense" postures, frequency of orienting, and frequency of agonistic behaviors. In addition, significant changes were seen in the time spent in proximity with other members of the group. The results are discussed both in terms of across-animal changes as well as with regard to social factors, rank in the hierarchy, and affiliative relationships.

摘要

在两个恒河猴群体中研究了苯丙胺对个体行为和社会行为的影响。在初始基线期之后,依次对每只动物进行为期3周的低剂量慢性药物给药。在每个药物给药期之间收集新的基线数据。在给予苯丙胺期间,以下行为显著增加:“紧张坐姿”的时间、定向频率和攻击行为频率。此外,与群体中其他成员接近的时间也出现了显著变化。从动物个体间的变化以及社会因素、等级制度中的地位和亲和关系等方面对结果进行了讨论。

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